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中文
Exon 2通过CRISPR/Cas9技术用三个shRNA导向序列靶向，这些序列为5'-ACACTATCTGGAGTCACTTA-3', 5'-CTACCTAGTAGCCAAGACTG-3', 和5'-AGTCATCTGGAAGATGGTGC-3'。有一只杂交鼠（founder mouse）出现了Exon 2内插入一个G碱基的变异(c.301_302insG)，导致了框架突变和过早终止。(来源：J:291290)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
