Prkn^rs13482876-G

Most mouse strains, including BALB/c, C57BL/6, and 129S, have this G variant of SNP rs13482876 coding for glutamic acid at position 398. C3H/HeJ, A/J, CBA/J, DBA/2J and PWK/PhJ mice exhibit a G-to-C transversion that results in an amino acid substitution of glutamic acid with glutamine at position 398 (p.E398Q). That mutation is synonymous with the E399Q mutation observed in human parkin. (J:160271)