Exon 3周围标记有loxP位点(loxP区大小为0.9kb),通过Flp酶介导去除了选择标记后,获得了条件性等位基因。随后,Cre酶介导的重组事件移除了Exon 3。(来源:J:147112)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入,基因内删除
--
1
5
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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