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中文
在B1-8hi小鼠的VH186.2-DFL16.1-JH2基因组DNA中，Leu33的TTG密码子被替换为TGG(Trp)，然后B1-8的生殖细胞片段被克隆到一个靶向载体中，通过电穿孔技术导入Bruce4 ES细胞进行同源重组。杂交小鼠产生后，通过与CAG-Flp转基因小鼠杂交去除诺如抗性基因(neor)。(来源：J:260241)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
