Nle1^rs13468707-T

This is the major variant of SNP rs13468707 (c.538G>A substitution leading to p.I180V) in exon 6 and codes for the wild-type evolutionary conserved isoleucine. The T variant is found in the 129P2/OlaHsd, 129S1/SvImJ, 129X1/SvJ, 129S5SvEvBrd, BTBR T+ TF/J, C3H/HeJ, CAST/EiJ, CBA/J, LP/J, PWD/PHJ, PWK/PhJ, SPRET/EiJ, and WSB/EiJ strains. This SNP is the equivalent of the well-documented human SNP rs2820949. (J:193532)