Exons 2和3被LoxP位点 flank(LoxP区大小:3.9kb)。正向选择标记由FRT(Neomycin抗性-NeoR)和F3(Puromycin抗性-PuroR)位点环绕,分别插入到内含子1和内含子3中。通过Flp介导的重组移除了选择性元件。(来源:J:314544)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count