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中文
设计了质粒，用于在第7外显子插入N542S点突变（AAT>AGT）、V543V无义突变（GTT>GTC）和L544L无义突变（CTT>CTC）。N542S突变模拟了与晚发性阿尔茨海默病风险相关的错义变异（rs12488237 SNP，来源：J:101977）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
