这个靶向构建插入到了F3位点,包含了一个含polyadenylation信号但无起始密码子的诺卡因抗性(NeoR)基因座,以及CAG启动子元件(包含CMV早期增强子、鸡β-actin启动子和腺病毒内含子),还包括Acad10开放阅读框(基于NCBI的NM_028037_2),一个合成的polyadenylation信号,以及FRT位点。(来源:J:147112)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
Targeted
插入
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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