在第3外显子下游的所有变体中引入了终止密码子。通过Cre介导的重组,移除了插入在第3外显子下游的佛波酯选择性载体。这个等位基因影响的变体包括:所有6和7个跨膜域变异,以及MOR-1S(来源:J:243674)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6(Cg)-Tyrc-2J
Targeted
核苷酸替换
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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