在基因的第七外显子周围插入了LoxP位点。在内源性等位基因的第6和第8外显子之间插入了由弗里特座标伴随的诺姆卡宾筛选元件。通过弗里普介导的生殖细胞重组移除了诺姆卡宾元件。(来源:J:286991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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