CRISPR/Cas9技术针对特定外显子1设计,产生了一个在目标序列周围114个核苷酸的缺失,以及在目标序列下游381个核苷酸的381个插入。 Western blot结果显示睾丸提取物中未检测到蛋白质。(来源:J:287082)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 X DBA/2)F1 x C57BL/6
Endonuclease-mediated
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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