Hmgcs2^em1Wilh

CRISPR/cas9 mediated recombination created a 647 bp deletion spanning most of exon 2 and part of intron 2. The deletion results in a stop codon seven codons after the breakpoint. Immunofluorescence analysis confirmed the absence of expression in ovaries and liver from E14.5 homozygous embryos. (J:285178)