在exon 1的5' UTR区域插入了一个loxP-和FRT引导的诺卡因抗性基因座。额外的loxP位点被插入到内含子1中。通过Flp介导的重组去除了选择性基因座,剩下exon 1的0.7kb区域是可剪接的。(来源:J:286963)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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