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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Cyp2c
tm1104Arte
Alias:
Del(19Cyp2c55-Cyp2c70)Arte
Cyp2c
KO
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基础信息
表型特征
文献报道
通过Cre介导的重组,在Cyp2c55内6号染色体上的胸苷激酶表达元件、羟氨苄青霉素抗性元件、LoxP位点、Lox5171和FRT位点,以及插入的f3启动子、LoxP位点、诺卡霉素抗性基因,以及Cyp2c70内1号染色体上删除的胸苷激酶表达元件,这些元件间原本的序列被去除了。(J:241121)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
6404559
C57BL/6NTac
Targeted
Insertion, Intergenic deletion
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5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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