在第3外显子上游插入了一个loxP位点,该位点位于起始密码子ATG之后。在第4编码序列的下游,插入了一个3'有FRT标记的诺卡因抗性元件,也带有loxP位点。通过Flp介导的重组,去除了选择性元件,使得编码序列得以去除了loxP标记。(来源:J:286157)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
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1
7
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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