在第3外显子中插入了276位氨基酸的亮氨酸到异亮氨酸突变。此外,上游插入了loxP位点,随后在第3外显子下游插入了FRT引导的诺卡因选择性载体和第二个loxP位点。通过Flp介导的重组移除了诺卡因选择性载体,而Cre介导的重组则删除了突变的第3外显子。(来源:J:285924)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
17
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部