在15-23号外显子被替换成新霉素选择标记元件。 Western blot结果显示,纯合小鼠肝脏、子宫和卵巢的提取物中没有蛋白质表达。免疫组化分析进一步证实了这些部位的肾上皮细胞、卵巢、输卵管和子宫中也未检测到蛋白质。(来源:J:286338)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入,基因内删除
--
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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