这个来自TCPR1524项目的等位基因是在表观基因组学中心通过电穿孔,用带有CTCTCAAAGGTTCTCCTGCG和TTATTATACCATAGTACAGT这两条特定引物RNA的Cas9核糖核酸复合物生成的。这些引物设计针对关键区域的5'和3'端。这导致了chr14:7629190-57629711位置一个522bp的缺失(GRCm38建库)。(来源:J:265051)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
不确定
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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