CRISPR/Cas9基因编辑技术用于在exon 2中产生一个62bp的缺失,包括起始密码子。qRT-PCR、免疫印迹分析和免疫荧光染色确认了来自纯合无卵母细胞的卵母细胞中内源性转录物和编码蛋白的缺失。(来源:J:284116)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
CD-1
Endonuclease-mediated
基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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