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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Col1a1
tm1(tetO/CMV-Lep)Rll
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基础信息
表型特征
文献报道
RCME在KH2细胞中插入了一个包含四环素响应元件和CAG启动子的 cassette,驱动小鼠Leptin基因的诱导性表达,后面跟着hygromycin B的选择标记基因。(来源:J:283599)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6393313
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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