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中文
在第2外显子上游插入了一个FRT-loxP-neo-FRT-LoxP的 cassette，同时在第5和6编码序列间插入了一个loxP位点。通过FLP介导的重组移除了含Frt标签的neo基因 cassette，随后在生殖细胞中通过Cre介导的重组，删除了序列2-5。 Western blot结果显示，来自E18纯合突变小鼠海马神经元原代培养物中，蛋白表达完全缺失。(来源：J:284998)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
