3号外显子和4号外显子由LoxP位点 flank,而阳性选择标记则由FRT(NeoR)和F3(PuroR)位点 flank,分别插入在2号内含子和4号内含子中。通过Flp介导的重组,这些选择标记被移除。(来源:J:253621)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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