这个Ai27特异性构建经过修改,包含:CAG启动子,FRT位点,loxP位点,终止子,三个poly(A)序列,再次的loxP位点,FRET驱动的TFP供体(仅连接vinculin头部,单分子的 teal 发光蛋白1,mTFP1,和vinculin尾部),WPRE,牛生长激素的poly(A)序列,attB位点,PGK启动子,FRT位点,以及诺卡因抗性基因座和attP位点。整个序列被插入在1号和2号外显子之间。(来源:J:275566)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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