包含EGFP报告基因、polyadenylation信号和F3介导的 puromycin抗性基因座的靶向载体被插入到exon 2,导致exon 2部分缺失,同时exons 3和4也被删除。通过Flp介导的重组,去除了含FRT标记的puro cassette。(来源:J:236888)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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