Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
基因编辑小鼠
Bdnf
tm1.1Xen
Alias:
Met68BDNF KI
BDNF
met
Need animal model construction services?
Click here >>
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
基础信息
表型特征
文献报道
第9外显子被替换成一个带有floxed Neo抗性标记的 cassette,同时对第9外显子进行了一处核苷酸替换,从GCT变为ATG,导致第68位的甲硫氨酸被缬氨酸取代。这种突变模拟了与精神类疾病关联的人类多态性。随后,通过Cre介导的重组移除了选择性标记(cassette)。(来源:J:284662)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6392346
C57BL/6NJcl
Targeted
Insertion, Nucleotide substitutions
--
1
2
3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部