Slc9a6^em1Moro

Plasmids encoding guide RNA (ATG GCT GGG GCT CGG CGC GGC TGG CGG CTG TCG) were designed to introduce guanine to thymine point mutation in exon 1. The resulting exon 1 harbors an alanine to serine mutation at amino acid position 11 (A11S). There are no known off-target sites present. The A11S mutation in orthologous to the human A9S mutation found in Christianson syndrome patients. (J:284697)