这个随机整合的转基因编码了一种带膜的鸡卵白(利用小鼠H2-Db的跨膜域)版本,其中嵌入了额外的T细胞抗原表位。这些额外的表位包括2W1S(EEAWGALANWAVDSA),它能作为自身抗原(2W)。表达由CAG(β-actin)启动子驱动。(来源:J:175217)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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