在exon 1的位置Q156插入了100个CAG重复,同时在CAG重复序列上游422bp的位置有一个G转换为A的限制性内切酶位点。通过Flp介导的重组,去除了在修改后的exon 1下游插入的FRT标记的诺卡因抗性 cassette。(来源:J:283871)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Single point
--
1
3
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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