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中文
Exon 2被通过同源重组的方式替换为一个包含loxP、frt-neo-frt-loxP靶向载体，这个载体带有Cre介导的重组系统。结果导致Exon 2被去除，产生了一个早发性终止密码子。 Western blot分析证实了来自E14.5胚胎的鼠胚胎成纤维细胞中没有蛋白表达。(来源：J:282438)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
