CRISPR/Cas9技术产生了一个37bp的缺失,位置在13号外显子,影响了仅从13号外显子转录的睾丸Ace基因。用于转染的sgRNA序列是:5'-GGCCAAGGTTGGGCTACTCC-3'和5'-TCTTTCTGCTGCTCTGCTGT-3',出自文献(J:279308)。
Basic Information
C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count