将靶向构建插入到一个CAGGS启动子(CAG)位点,这个位置包含一个可删除的PGK-puromycin终止子(LSL)序列,一个带有N端FLAG和myc标签的mouse Dnd1基因克隆,以及一个frt位点。当Cre介导去除终止子后,这个小基因会持续以CAG启动子驱动的模式表达带有FLAG和myc标签的Dnd1基因。(来源:J:281756)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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