靶向载体设计为在exon 2上游插入一个loxP位点,接着是FRT-PGK-neo-pA-SD-IS-FRT的元件,后面跟着exon 2下游的第二个loxP位点。SD是splice donor序列,IS是一个54bp的不稳定性信号。(来源:J:283234)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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