在第4个内含子插入了loxP-FRT-PGK-Neo-PGKpA-FRT的 cassette,然后在第5个内含子放置了一个loxP位点。通过Flp介导的重组,去除了含FRT标记的neo cassette,使得第5个外显子成为可调节的。(来源:J:282819)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count