这个IMPC的等位基因是在巴约医学院通过注入Cas9蛋白和四个引导序列(TGGTTTAGTGTTGTACCTTATGG, CCAAGACATCCAATCTCATAAGA, GTAAACAACTAGAGAATTCTTGG, CCAAAAAGGGAGCTACAAATGTG)产生的,导致了外显子的缺失。(来源:J:265051)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
基因内删除
不确定
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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