这个来自TCPR1478项目的等位基因是在表观基因组学中心通过电穿孔,将Cas9核糖核酸蛋白复合物与具有GCTTAGTGACTGATCGCAGT作为5'端引导RNA和CAAAACAACTACGGAGTTAG作为3'端引导RNA的单链RNA,针对一个关键区域的靶标生成的。这导致了chr12:51388915-51390535位置的1621bp缺失(GRCm38建库)。(来源:J:265051)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
不确定
1
--
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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