RMCE在KH2细胞中替换了FRT座标记的neo cassette,替换为包含一个splice接受器、polyadenylation序列和tetacycline启动子,驱动诱导性表达一个由HA标签标记的小鼠Ccne1的cDNA,后面跟着另一个polyadenylation序列和hygromycin抗性 cassette,其中也包含FRT座。(来源:J:281613)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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