RMCE在KH2细胞中替换了FRT座标记的neo cassette,替换为包含一个splice接受器、polyadenylation序列和tetacycline启动子,驱动诱导性表达一个由HA标签标记的小鼠Ccne1的cDNA,后面跟着另一个polyadenylation序列和hygromycin抗性 cassette,其中也包含FRT座。(来源:J:281613)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count