6-8号外显子由loxP序列 flank,通过Cre介导的重组在生殖细胞中删除了这些区域。 Western blot结果显示肾组织中没有检测到蛋白质(来源:J:279853)
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Exons 6-8 were flanked by loxP sites. Cre-mediated recombination deleted exons 6-8 in the germline. Western blot analysis confirmed the absence of protein in kidney tissue. (J:279853)