在exon 4上游插入了一个loxP位点。exon 5被修改过的exon 5替换,编码了在第310位由天冬氨酸替换为氮酸的氨基酸(D310N)。下游插入了一个FRT引导的诺卡因抗性基因座,带有5'的loxP位点。(来源:J:267760)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Nucleotide substitutions
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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