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中文
CRISPR/Cas9基因编辑技术通过两个sgRNAs（针对GGGCCATACTCCACTTGGAAA和ACCGCGGTAAGCTGCTCCCC）对基因组进行操作，产生一个56个碱基对的删除，覆盖了exon 1编码区的最后三个核苷酸以及1号内含子5'端的内含子序列（GRCm39:chr18:14839387-14839442）。这个删除导致exon 1的异常剪接，形成一个非编码的内含子片段，随后与exon 2连接，继续进行剪接。来源：J:279007
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
