CRISPR对Zfp418基因的exon 2位点进行了编辑,产生了突变。基因分型结果显示,这些突变主要为缺失(2-12bp),也有少量插入(2-3bp),所有突变都发生在目标序列中。#符号代表了这些基因在敲除创始群体中所有等位基因的集合。(来源:J:251673)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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