Aars2^tm2.1Htyy

A nucleotide change T to A at position 2264, resulting in a valine to glutamate change at amino acid 755, was introduced in exon 17. A neomycin resistance gene flanked by loxP sites was also introduced into intron 17. Cre-mediated recombination in the ES cells removed the selection cassette. (J:257856)