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中文
在exon 16的2230-2231位点，从胸腺嘧啶(T)替换成鸟嘌呤(G)的核苷酸变化，导致第744位的 cysteine 被替换为 alanine。同时，intron 17内插入了由FRT位点 flank 的新霉素抗性基因。通过ES细胞中的Flp介导的重组，去除了选择性载体。(来源：J:257856)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
