这个等位基因是通过CRISPR/Cas9技术,使用sgRNA和模板寡核苷酸生成的。在丝氨酸密码子1712处删除了两个碱基,导致阅读框移位和一个早闭合终止密码子。(来源:J:278360)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
基因内删除
--
1
13
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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