在第3-5外显子周围插入了loxP位点和FRT引导的氨苄西林抗性基因,同时在第2内含子和第5内含子分别插入了F3引导的puromycin抗性基因。通过Flp介导的重组,选择标记被移除,使得3-5外显子区域被去除了选择性标记。(来源:J:279270)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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