在胚胎干细胞(ES)细胞中,通过同源重组技术,我们插入了一个IRES-FlpO-loxP2272-ACE-Cre POII NeoR-loxp2272的 cassette,它位于Slc6a4/Sert基因的TAA终止密码子之后。这个loxP2272-ACE-Cre POII NeoR-loxp2272区域能够自我剪切。(来源:J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac x C57BL/6J
Targeted
插入
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1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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