这个靶向构建包含一个位于第3外显子上游的loxP位点,一个连接到第4外显子3'端的EYFP报告基因,一段polyA,以及一个由FRT序列包裹的诺卡因 cassette,后面跟着另一个loxP位点。通过Flp介导的重组,FRT标记的诺卡因 cassette被移除。(来源:J:278343)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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