使用了一种靶向载体,包含Flpo-poly(A)序列和一个由loxP位点标记的PGK/Em7-Neo元件,用于替换基因exon 1中的107bp片段。通过Cre介导的重组,去除了含有的floxed neo cassette(来源:J:198264)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入,基因内删除
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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