这个靶向构建在编码钙依赖性蛋白激酶K2 ATP 结合区域的exons 2-4外周序列中插入了两个loxP位点,同时还包括了另一个由loxP位点 flank 的neo cassette。(来源:J:136219)
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The targeting construct introduced two loxP sites into the gene flanking exons 2-4, which encode elements of the CaMKK2 ATP binding domain, as well as the neo cassette, also flanked by loxP sites. (J:136219)