使用含有Frt内切酶靶向序列、Neo基因和3xFlag标签的构建,通过同源重组在ES细胞中将Flag标签插入Bach2基因的起始甲硫氨酸位置。随后,这些转基因小鼠与FLPe小鼠杂交去除Neo基因(来源:J:272661)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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