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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Vim
tm1Sibg
Alias:
Vim
SA
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基础信息
表型特征
文献报道
通过靶向诱变技术,产生了在编码蛋白的vimentin头部区域多个位置替换为Ala的Ser到Ala的突变,包括exon 1中的第6、24、38、46、55、64、65、71、72和82、86位。 (来源:J:276637)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6355955
129P2/OlaHsd
Targeted
核苷酸替换
--
1
2
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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